⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28048586 | 0.98 | — | — | |
| Methylene Chloride SCHEMBL7089348 | 0.94 | — | — | |
| SCHEMBL1170450 | 0.81 | ALDH1A1 (0.38) | — | |
| SCHEMBL7088318 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL6230305 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL28069297 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL7253131 | 0.79 | ADORA2A (0.35) | — | |
| SCHEMBL10581425 | 0.79 | ALDH1A1 (0.36) | — | |
| SCHEMBL2909312 | 0.79 | F2 (0.31) | — | |
| Potassium Ion SCHEMBL2809238 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3774749-B1 | METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE | BAYER AG (DE) | 2024-11-20 | — | — | EP | claimed |
| CN-117903078-A | Amide derivative containing 3, 4-dichloro isothiazole, preparation method and application thereof | 南开大学 | 2024-04-19 | — | — | CN | claimed |
| CN-112004806-B | Process for preparing 3, 4-dichloro-N- (2-cyanophenyl) -5-isothiazolecarboxamide | 拜耳公司 | 2023-10-13 | — | — | CN | claimed |
| CN-110719908-B | Process for preparing 3, 4-dichloro-N- (2-cyanophenyl) -5-isothiazolecarboxamide | 拜耳股份公司 | 2023-05-26 | — | — | CN | claimed |
| US-11339137-B2 | Method for producing 3,4-dichloro-N-(2-cyanophenyl)-5-isothiazolecarboxamide | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | claimed |
| US-11220487-B2 | Process for preparing 3,4-dichloro-n-(2-cyanophenyl)-5-isothiazolecarboxamide | BAYER AKTIENGESELLSCHAFT (DE) | 2022-01-11 | — | — | US | claimed |
| EP-3638653-B1 | PROCESS FOR PREPARING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE | BAYER AG (DE) | 2021-12-15 | — | — | EP | claimed |
| CN-112939980-A | 3, 4-dichloroisothiazole heterocyclic purine derivatives and preparation method and application thereof | 南开大学 | 2021-06-11 | — | — | CN | claimed |
| US-20210163430-A1 | METHOD FOR PRODUCING 3,4-DICHLORO-N-(2-CYANOPHENYL)-5-ISOTHIAZOLECARBOXAMIDE | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2021-06-03 | — | — | US | claimed |
| CN-112441990-A | Bisamide compound containing 3, 4-dichloroisothiazole heterocycle, and preparation method and application thereof | 江西天宇化工有限公司 | 2021-03-05 | — | — | CN | claimed |
| EP-1261592-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-04 | — | — | EP | claimed |
| US-20020091067-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2002-07-11 | — | — | US | claimed |
| WO-2002051822-A2 | ISOTHIAZOLECARBOXAMIDES AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-07-04 | — | — | WO | claimed |
| US-6372692-B1 | PESTICIDES, FUNGICIDES, INSECTICIDES, NEMATOCIDES, AND MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-16 | — | — | US | claimed |
| US-6310005-B1 | FUNGICIDES, PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | claimed |
| WO-2001077090-A2 | ISOTHIAZOLE DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-18 | — | — | WO | claimed |
| US-6277791-B1 | PREVENT PLANT DAMAGE; FUNGICIDE, BACTERICIDE, VIRICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | claimed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | claimed |
| WO-2001029014-A1 | ISOTHIAZOLE-5-CARBOXYLIC ESTERS AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-04-26 | — | — | WO | claimed |
| US-6191155-B1 | MICROBIOCIDES; PESTICIDES; PLANT SAFENING AGENTS; FUNGICIDES; MITICIDES; BACTERICIDES; HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-20 | — | — | US | claimed |