Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170450 | 0.79 | ALDH1A1 (0.38) | MAPK1HTTTSHRRXFP1POLB | |
| SCHEMBL1720501 | 0.79 | — | — | |
| SCHEMBL7088318 | 0.77 | — | — | |
| SCHEMBL10581425 | 0.77 | ALDH1A1 (0.36) | MAPK1HTTTSHRRXFP1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6230305 | 0.77 | ALDH1A1 (0.36) | MAPK1HTTTSHRRXFP1ALDH1A1 | |
| SCHEMBL7253131 | 0.77 | ADORA2A (0.35) | — | |
| SCHEMBL22263172 | 0.76 | CA1 (0.31) | — | |
| Potassium Ion SCHEMBL2809238 | 0.76 | — | — | |
| Methylene Chloride SCHEMBL7089348 | 0.74 | — | — | |
| Isopropylamine SCHEMBL9466355 | 0.74 | ALDH1A1 (0.35) | HTTTSHRALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1260140-B1 | Isothiazolecarbamide derivatives for crop protection | BAYER CROPSCIENCE AG (DE) | 2010-08-18 | — | — | EP | claimed |
| US-20070232670-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2007-10-04 | — | — | US | claimed |
| US-7157481-B2 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | BAYER AKTIENGESELLSCHAFT (DE) | 2007-01-02 | — | — | US | claimed |
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2005-07-21 | — | — | US | claimed |
| US-20040044054-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2004-03-04 | — | — | US | claimed |
| EP-1114038-B1 | ISOTHIAZOLE CARBOXYLIC ACID AMIDES | BAYER CROPSCIENCE AG (DE) | 2003-12-03 | — | — | EP | claimed |
| US-6642181-B2 | 3,4-dichloro-isothiazole-5-carboxamide derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 2003-11-04 | — | — | US | claimed |
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | NIHON BAYER AGROCHEM, K.K. (JP) | 2003-09-18 | — | — | US | claimed |
| EP-1261592-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2002-12-04 | — | — | EP | claimed |
| US-20020091067-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | ASSMANN LUTZ (DE) | 2002-07-11 | — | — | US | claimed |
| US-6372692-B1 | PESTICIDES, FUNGICIDES, INSECTICIDES, NEMATOCIDES, AND MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2002-04-16 | — | — | US | claimed |
| US-6310005-B1 | FUNGICIDES, PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | claimed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | claimed |
| US-20220000117-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2022-01-06 | — | — | US | disclosed |
| EP-3878278-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | Kumiai Chemical Industry Co., Ltd. (JP) | 2021-09-15 | — | — | EP | disclosed |
| CN-104974150-B | A kind of carboxamidine derivatives of 3,4 2 chloroisothiazole 5 and its production and use | 南开大学 | 2018-03-09 | — | — | CN | disclosed |
| US-6310005-B1 | FUNGICIDES, PESTICIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | disclosed |
| US-6277791-B1 | PREVENT PLANT DAMAGE; FUNGICIDE, BACTERICIDE, VIRICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-21 | — | — | US | disclosed |
| WO-2001055124-A1 | ISOTHIAZOLECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS MICROBICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 2001-08-02 | — | — | WO | disclosed |
| US-5240951-A | Isothiazolecarboxylic acid derivatives, rice blast control agents containing the same as active ingredients, and rice blast control method applying the control agents | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1993-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220000117-A1 | METHOD FOR CONTROLLING DISEASES IN SMALL GRAIN CEREALS, SEED OF SMALL GRAIN CEREALS, AND METHOD FOR SUPPRESSING LODGING DAMAGE IN SMALL GRAIN CEREALS | LCT, BROX, GYS2 | F2 4441/4885LMNA 2910/4885MAPK1 1976/4885 |
| US-20050159464-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, AADAC, CBR3 | F2 1539/4885LMNA 4856/4885MAPK1 3768/4885 |
| US-20070232670-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, AADAC, CBR3 | F2 1539/4885LMNA 4856/4885MAPK1 3768/4885 |
| US-20020091067-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, CBR3, AADAC | F2 1878/4885LMNA 4852/4885MAPK1 1703/4885 |
| US-20030176477-A1 | Isothiazolecarboxylic acid derivatives and their use as microbicides | IFNG, MPO, CD14 | F2 2644/4885LMNA 4750/4885MAPK1 3975/4885 |
| US-20040044054-A1 | Isothiazole carboxylic acid amides and the application thereof in order to protect plants | CAT, CBR3, AADAC | F2 1878/4885LMNA 4852/4885MAPK1 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.