Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924156 | 0.96 | CHRM1 (0.45) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL17206716 | 0.93 | CHRM1 (0.43) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL9924432 | 0.93 | CHRM1 (0.43) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL17206712 | 0.92 | CHRM1 (0.43) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL17206703 | 0.89 | CHRM1 (0.41) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL9924076 | 0.88 | CHRM1 (0.41) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL9923856 | 0.86 | CHRM1 (0.42) | CHRM1MCHR1POLBALDH1A1CYP2C9 | |
| SCHEMBL9924158 | 0.86 | CHRM1 (0.42) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL9924154 | 0.85 | CHRM1 (0.40) | TAS1R3TAS1R1TAS1R2CHRM1MCHR1 | |
| SCHEMBL9924247 | 0.85 | TAS1R3 (0.48) | TAS1R3TAS1R1TAS1R2MCHR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |