Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17206716 | 1.00 | CHRM1 (0.43) | CHRM1TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL17206712 | 0.99 | CHRM1 (0.43) | CHRM1TAS1R3TAS1R1TAS1R2MAPT | |
| SCHEMBL9924156 | 0.97 | CHRM1 (0.45) | CHRM1TAS1R3TAS1R1TAS1R2MCHR1 | |
| SCHEMBL17206707 | 0.93 | TAS1R3 (0.43) | CHRM1TAS1R3TAS1R1TAS1R2NPC1 | |
| SCHEMBL17206703 | 0.90 | CHRM1 (0.41) | CHRM1TAS1R3TAS1R1TAS1R2MCHR1 | |
| SCHEMBL9924076 | 0.89 | CHRM1 (0.41) | CHRM1TAS1R3TAS1R1TAS1R2MCHR1 | |
| SCHEMBL17206722 | 0.87 | CHRM1 (0.41) | CHRM1TAS1R3TAS1R1TAS1R2MCHR1 | |
| SCHEMBL9923856 | 0.87 | CHRM1 (0.42) | CHRM1MAPTSMN1; SMN2MCHR1ALDH1A1 | |
| SCHEMBL9924158 | 0.87 | CHRM1 (0.42) | CHRM1TAS1R3TAS1R1TAS1R2MCHR1 | |
| SCHEMBL9924154 | 0.86 | CHRM1 (0.40) | CHRM1TAS1R3TAS1R1TAS1R2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |