Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 18/20 | 0.55 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17033958 | 0.92 | CHRM4 (0.57) | CHRM4CHRM2 | |
| SCHEMBL2056186 | 0.87 | CHRM4 (0.55) | CHRM4CHRM2 | |
| SCHEMBL547906 | 0.82 | CHRM4 (0.59) | CHRM4CHRM2 | |
| SCHEMBL7790074 | 0.82 | ME2 (0.42) | CHRM4CHRM2DPP4 | |
| SCHEMBL30516679 | 0.81 | KDM4E (0.44) | DPP4 | |
| SCHEMBL13279361 | 0.81 | CHRM4 (0.55) | CHRM4CHRM2 | |
| SCHEMBL2056147 | 0.81 | CHRM4 (0.57) | CHRM4CHRM2 | |
| SCHEMBL2056106 | 0.81 | CHRM4 (0.57) | CHRM4CHRM2 | |
| SCHEMBL13279873 | 0.80 | CHRM4 (0.59) | CHRM4CHRM2 | |
| SCHEMBL13279129 | 0.80 | CHRM4 (0.54) | CHRM4CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169240-B2 | Ketone linked benzothiazole inhibitors of endothelial lipase | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-10-27 | — | — | US | disclosed |