Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 6/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 3/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7522251 | 0.78 | DPP4 (0.40) | DPP4ELANEZDHHC20ZDHHC2CYP1A2 | |
| SCHEMBL7522465 | 0.76 | DPP4 (0.53) | DPP4ELANEZDHHC20ZDHHC2CYP1A2 | |
| SCHEMBL7521208 | 0.76 | ZDHHC20 (0.51) | DPP4ELANEZDHHC20ZDHHC2CYP1A2 | |
| SCHEMBL7525018 | 0.74 | CYP1A2 (0.41) | DPP4ELANEZDHHC20ZDHHC2CYP1A2 | |
| SCHEMBL17611943 | 0.74 | — | — | |
| SCHEMBL5468884 | 0.72 | — | — | |
| SCHEMBL7517117 | 0.71 | CTSS (0.51) | CYP1A2 | |
| SCHEMBL3928512 | 0.67 | DPP4 (0.41) | DPP4ELANEZDHHC20ZDHHC2CYP1A2 | |
| SCHEMBL19883438 | 0.64 | — | — | |
| SCHEMBL21680807 | 0.64 | DPP4 (0.46) | DPP4ELANEMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9487517-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2016-11-08 | — | — | US | disclosed |
| US-9169254-B2 | Spiroimidazolone derivative | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2015-10-27 | — | — | US | disclosed |