SCHEMBL17208145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13875295	0.87	PTGS2 (0.73)	PTGS2CDC42RAC1PTGS1PAK1
	SCHEMBL26234550	0.87	PTGS2 (0.51)	PTGS2CDC42RAC1PTGS1PAK1
	SCHEMBL24807886	0.86	PTGS2 (0.75)	PTGS2CDC42RAC1PTGS1PAK1
	SCHEMBL18133558	0.85	PTGS2 (0.79)	PTGS2CDC42RAC1PTGS1PAK1
	SCHEMBL12286244	0.83	PTGS2 (0.79)	PTGS2CDC42RAC1PTGS1PAK1
	Ketorolac SCHEMBL14891	0.83	PTGS2 (1.00)	PTGS2CDC42RAC1PTGS1PAK1
	Ketorolac SCHEMBL14892	0.83	PTGS2 (1.00)	PTGS2CDC42RAC1PTGS1PAK1
	Ketorolac SCHEMBL4103	0.83	PTGS2 (1.00)	PTGS2CDC42RAC1PTGS1PAK1
	Ketorolac SCHEMBL23466702	0.83	PTGS2 (1.00)	PTGS2CDC42RAC1PTGS1PAK1
	Ketorolac SCHEMBL2221913	0.82	PTGS2 (0.92)	PTGS2CDC42RAC1PTGS1PAK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.