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Sugi Predict / Targets / S100A10

S100A10

Protein S100-A10 · P60903 · S100A10 on Sugi Atlas →

1,716 patent compounds predicted against S100A10, 1,028 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL2232974 SCHEMBL2232974 0.65 17/20
SCHEMBL2299703 SCHEMBL2299703 0.70 15/20
SCHEMBL2233884 SCHEMBL2233884 0.67 15/20
SCHEMBL2235286 SCHEMBL2235286 0.67 14/20
SCHEMBL2232333 SCHEMBL2232333 0.66 14/20
SCHEMBL2234497 SCHEMBL2234497 0.69 13/20
SCHEMBL2298299 SCHEMBL2298299 0.67 13/20
SCHEMBL2230926 SCHEMBL2230926 0.66 13/20
SCHEMBL2231482 SCHEMBL2231482 0.58 13/20
SCHEMBL2235370 SCHEMBL2235370 0.53 13/20
SCHEMBL2233843 SCHEMBL2233843 0.66 12/20
SCHEMBL2236163 SCHEMBL2236163 0.66 11/20
SCHEMBL2295548 SCHEMBL2295548 0.55 11/20
SCHEMBL2236328 SCHEMBL2236328 0.54 11/20
SCHEMBL2234993 SCHEMBL2234993 0.65 10/20
SCHEMBL2233246 SCHEMBL2233246 0.55 10/20
SCHEMBL2234809 SCHEMBL2234809 0.65 9/20
SCHEMBL2234316 SCHEMBL2234316 0.53 9/20
SCHEMBL2232280 SCHEMBL2232280 0.68 8/20
SCHEMBL8776126 SCHEMBL8776126 0.47 8/20

Clinical trials — most relevant to S100A10 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Serum Calprotectin Level in Patients With Rheumatoid Arthritis and Osteoarthritis PHASE4UNKNOWN
Efficacy of Recombinant Human Clara Cell 10 Protein (rhCC10) Administered to Premature Neonates With Respiratory Distress Syndrome PHASE2COMPLETED
Dexmedetomidine and Magnesium Sulfate in the Reduction Cognitive Dysfunction in Geriatrics PHASE1RECRUITING
Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival PHASE1UNKNOWN
Biomarkers in Participants With Hidradenitis Suppurativa Receiving Guselkumab. EARLY_PHASE1WITHDRAWN
S100A8/A9 and Innate Immunity in Liver Disease nanUNKNOWN
S100A8 in Serum and Urine as a New Biomarker in Lupus Nephritis nanCOMPLETED
Neurological Prognostication of Patients in Therapeutic Hypothermia After Cardiac Arrest nanCOMPLETED
Protein S100B Versus Neutrophils/Lymphocytes Ratio in Early Prediction of Brain Injury nanCOMPLETED
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life nanCOMPLETED
Urine Concentration of S100B in Extremely Premature Infants nanCOMPLETED
Interventional Study for Detection of Prognosis of Blood Based Biomarkers in Intracerebral Hemorrhage nanNOT_YET_RECRUITING
GRINCH: Groningen Initiative on Reference Intervals in Children nanCOMPLETED
Evaluation of s100β, NSE and GFAP Levels in Renal Transplantation nanCOMPLETED
S100β and Neuron Specific Enolase Levels in Liver Transplantation nanCOMPLETED
A Role for RAGE/TXNIP/Inflammasome Axis in Alveolar Macrophage Activation During ARDS (RIAMA): a Proof-of-concept Clinical Study nanCOMPLETED
S100 Protein in Minor/Mild Traumatic Brain Injury nanCOMPLETED
Soluble Forms and Ligands of RAGE in ALI/ARDS (SoLiRAGE). nanCOMPLETED
OptiCal Study -Optimizing Fecal Calprotectin Monitoring: a Clinical Study Comparing CalproLab Against PhiCal and Evaluating Its Association With the Gut Microbiome nanCOMPLETED
Exercise and the Receptor for Advanced Glycation End Products (RAGE) nanCOMPLETED
Evaluation of the Role of Neurodegeneration in Schizophrenia nanCOMPLETED
Diagnostic Performance of the S100B Protein in the Prognosis of Patients With Mild Head Trauma With Risk of Complications in Patients Over 65 Years Old. nanUNKNOWN
Calprotectin, a Biomarker of COVID-19 Severity (CALPRO) nanWITHDRAWN
The Clinical Utility of Fecal Caprotectin and Lactoferrin in Patients Undergoing Capsular Endoscopy nanUNKNOWN
Early Prediction of Oral Cancer by S100A7 Immunohistochemistry Signature-based Assessment nanRECRUITING
S100B in the Care of Non-traumatic Headaches in the Emergency Department nanCOMPLETED
Evaluation of the Predictive Impact of Serum S100B and S100B Polymorphisms on Postoperative Cognitive Dysfunction and Delirium nanCOMPLETED
Using Routine Inflammatory and Metabolic Blood Tests (Bedside Included) to Predict Brain Injury in Children After Minor Head Trauma nanNOT_YET_RECRUITING
Single-center Transversal Observational Study on the Evaluation of S100B Changes in Subjects Attending the Emergency Department With Head Trauma nanRECRUITING
Screening for Prognostic Biomarkers of Severe Bell's Palsy in Adults nanRECRUITING

Related proteins — ESM-2 sequence neighbours (a S100A10 binder may also engage these)

ProteinNameSimilarity
P62504 — 1.000 P62504 →
P60902 — 1.000 P60902 →
P04163 — 1.000 P04163 →
Q6SQH4 — 1.000 Q6SQH4 →
P27003 — 0.973 P27003 →
P08207 — 0.940 P08207 →
P05943 — 0.938 P05943 →
Q96BS2 — 0.928 Q96BS2 →
SRI Sorcin 0.921 landscape →
A0JN27 — 0.921 A0JN27 →
Q13888 — 0.920 Q13888 →
Q5R4U9 — 0.920 Q5R4U9 →
Q9JIB4 — 0.919 Q9JIB4 →
Q6P1K8 — 0.918 Q6P1K8 →
Q2TBV5 — 0.918 Q2TBV5 →
Q7RTP6 — 0.917 Q7RTP6 →
PAICS Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase 0.917 landscape →
Q9JKL5 — 0.916 Q9JKL5 →
P33764 — 0.914 P33764 →
Q64119 — 0.912 Q64119 →
Q5F398 — 0.912 Q5F398 →
DCUN1D2 DCN1-like protein 2 0.912 landscape →
Q7L5Y9 — 0.912 Q7L5Y9 →
Q5R532 — 0.911 Q5R532 →
Q5RB59 — 0.911 Q5RB59 →
Q5TA45 — 0.911 Q5TA45 →
P51583 — 0.910 P51583 →
Q4R9A8 — 0.910 Q4R9A8 →
O54984 — 0.910 O54984 →
ERBB4 Receptor tyrosine-protein kinase erbB-4 0.910 landscape →