Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 3/20 | 0.32 |
| ▸ | APP | P05067 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10815076 | 1.00 | EGLN1 (0.37) | EGLN1LDHASRRNFE2L2HCAR2 | |
| SCHEMBL6284324 | 0.81 | POLB (0.50) | NFE2L2HCAR2KEAP1GSK3BTSHR | |
| SCHEMBL4534469 | 0.77 | CASP1 (0.39) | EGLN1LDHASRRHCAR2POLB | |
| SCHEMBL4534473 | 0.77 | CASP1 (0.39) | EGLN1LDHASRRHCAR2POLB | |
| SCHEMBL1259298 | 0.75 | — | — | |
| SCHEMBL1259300 | 0.75 | — | — | |
| SCHEMBL6916368 | 0.72 | — | — | |
| SCHEMBL15756156 | 0.71 | — | — | |
| Propionic Acid SCHEMBL28002953 | 0.71 | FFAR3 (0.48) | EGLN1HCAR2TSHRLMNATP53 | |
| SCHEMBL6833025 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9327281-B2 | Carbon-dioxide compound and catalyst | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-03 | — | — | US | disclosed |
| US-9327281-B2 | Carbon-dioxide compound and catalyst | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-05-03 | — | — | US | disclosed |
| US-20150306590-A1 | CARBON-DIOXIDE COMPOUND AND CATALYST | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-10-29 | — | — | US | disclosed |
| US-20150306590-A1 | CARBON-DIOXIDE COMPOUND AND CATALYST | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306590-A1 | CARBON-DIOXIDE COMPOUND AND CATALYST | MT-CO2, CNOT9, SCO2 | EGLN1 4089/4885LDHA 1483/4885SRR 4802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.