Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 12/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706434 | 0.75 | DGAT1 (0.36) | KDRDGAT1 | |
| Hydrochloric Acid SCHEMBL6207073 | 0.73 | DGAT1 (0.36) | KDRDGAT1 | |
| SCHEMBL239135 | 0.72 | KDR (0.40) | PDE3BPDE3AKDRDGAT1 | |
| SCHEMBL239290 | 0.72 | KDR (0.39) | KDRDGAT1 | |
| SCHEMBL1074481 | 0.71 | DGAT1 (0.36) | KDRDGAT1 | |
| SCHEMBL2755265 | 0.69 | PIM1 (0.42) | KDR | |
| SCHEMBL14905764 | 0.67 | PDE3B (0.39) | PDE3BPDE3AHCAR1 | |
| SCHEMBL17645606 | 0.65 | DGAT1 (0.36) | KDRDGAT1 | |
| SCHEMBL31593702 | 0.64 | GABRP (0.41) | KDR | |
| SCHEMBL29792823 | 0.63 | DYRK1A (0.39) | KDRDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406250-A1 | INHIBITORS OF AKT ACTIVITY | Merck Sharp & Dohme Corp. (US) | 2012-01-18 | — | — | EP | disclosed |