Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.73 |
| ▸ | MAPT | P10636 | 8/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.73 |
| ▸ | RAB9A | P51151 | 5/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868872 | 0.87 | MAPT (0.65) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL1227106 | 0.86 | MAPT (1.00) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL13913968 | 0.81 | MAPT (0.89) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL6003482 | 0.81 | MAPT (0.89) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28618511 | 0.80 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL28618513 | 0.80 | MAPT (0.57) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL14965061 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL14965059 | 0.80 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL17208843 | 0.79 | MAPT (0.73) | ALDH1A1MAPTKMT2AMEN1RAB9A | |
| SCHEMBL24851242 | 0.79 | RAB9A (0.69) | ALDH1A1MAPTKMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170168041-A1 | Polymers And Oligomers With Aggregation-Induced Emission Characteristics For Imaging And Image-Guided Therapy | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-06-15 | — | — | US | disclosed |
| US-20170168041-A1 | Polymers And Oligomers With Aggregation-Induced Emission Characteristics For Imaging And Image-Guided Therapy | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2017-06-15 | — | — | US | disclosed |
| WO-2015163817-A1 | POLYMERS AND OLIGOMERS WITH AGGREGATION-INDUCED EMISSION CHARACTERISTICS FOR IMAGING AND IMAGE-GUIDED THERAPY | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2015-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170168041-A1 | Polymers And Oligomers With Aggregation-Induced Emission Characteristics For Imaging And Image-Guided Therapy | MAPT, FUS, CLTB | ALDH1A1 2973/4885MAPT 1/4885KMT2A 4688/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.