Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209265 | 0.85 | EPHX1 (0.49) | TRPV1MEN1KMT2AEPHX1 | |
| SCHEMBL17209263 | 0.81 | CASR (0.54) | MEN1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL17209261 | 0.80 | NAMPT (0.53) | TRPV1ALDH1A1 | |
| SCHEMBL17209264 | 0.78 | MAPT (0.50) | TRPV1MEN1ALDH1A1KMT2AHPGD | |
| SCHEMBL1806012 | 0.78 | CYP2A6 (0.50) | MEN1KMT2A | |
| SCHEMBL1397891 | 0.76 | CYP2A6 (0.49) | — | |
| SCHEMBL24575982 | 0.75 | TSHR (0.71) | TRPV1MEN1ALDH1A1KMT2ATSHR | |
| SCHEMBL1397414 | 0.75 | NAMPT (0.67) | TRPV1MEN1KMT2APLAAT3PLAAT5 | |
| SCHEMBL7433359 | 0.75 | CYP2A6 (0.53) | MEN1KMT2A | |
| SCHEMBL13355180 | 0.74 | TRPV1 (0.47) | TRPV1MEN1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |