Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17202890 | 0.87 | TRPV1 (0.62) | TRPV1ALDH1A1 | |
| SCHEMBL17209263 | 0.85 | CASR (0.54) | NAMPTALDH1A1 | |
| SCHEMBL17209265 | 0.82 | EPHX1 (0.49) | NAMPTTRPV1 | |
| SCHEMBL17209264 | 0.80 | MAPT (0.50) | NAMPTTRPV1ALDH1A1 | |
| SCHEMBL17209262 | 0.80 | TRPV1 (0.47) | TRPV1ALDH1A1 | |
| SCHEMBL2846746 | 0.77 | TRPV1 (0.69) | TRPV1ALDH1A1 | |
| SCHEMBL17202845 | 0.75 | TRPV1 (0.76) | TRPV1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL17203184 | 0.74 | TRPV1 (0.76) | TRPV1ALDH1A1MTNR1AMTNR1B | |
| SCHEMBL1806012 | 0.73 | CYP2A6 (0.50) | NAMPT | |
| SCHEMBL6567251 | 0.73 | ALDH1A1 (0.70) | TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |