Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CLK1 | P49759 | 2/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | FPR2 | P25090 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209265 | 0.86 | EPHX1 (0.49) | KMT2AMEN1NAMPTHDAC1POLB | |
| SCHEMBL17202891 | 0.85 | ALDH1A1 (0.57) | KMT2AKDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL17209261 | 0.85 | NAMPT (0.53) | ALDH1A1NAMPT | |
| SCHEMBL17209262 | 0.81 | TRPV1 (0.47) | KMT2AMEN1ALDH1A1EPHX1 | |
| SCHEMBL16562237 | 0.78 | EPHX1 (0.74) | CASRKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL17209264 | 0.77 | MAPT (0.50) | KMT2AKDM4EMEN1ALDH1A1NAMPT | |
| SCHEMBL1806012 | 0.77 | CYP2A6 (0.50) | KMT2AMEN1RAB9ANAMPTHDAC1 | |
| SCHEMBL5338788 | 0.75 | KMT2A (0.56) | KMT2AKDM4EMEN1ALDH1A1NPC1 | |
| SCHEMBL16562080 | 0.75 | NPC1 (0.77) | CASRKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL12113008 | 0.74 | FPR2 (0.61) | CASRKMT2AMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015162216-A1 | BIARYL AMIDE OR UREA DERIVATIVES AS TRPV1 LIGANDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2015-10-29 | — | — | WO | disclosed |