Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 6/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | MAOA | P21397 | 3/20 | 0.66 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.66 |
| ▸ | XDH | P47989 | 3/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | SLCO2B1 | O94956 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CA12 | O43570 | 1/20 | 0.66 |
| ▸ | CA2 | P00918 | 1/20 | 0.66 |
| ▸ | CA4 | P22748 | 1/20 | 0.66 |
| ▸ | CA7 | P43166 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HES1 | Q14469 | 2/20 | 0.64 |
| ▸ | FANCF | Q9NPI8 | 2/20 | 0.64 |
| ▸ | KDM1A | O60341 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20802174 | 0.83 | KDM4E (0.64) | P4HBKDM4EMAOAEPHX2XDH | |
| SCHEMBL13393799 | 0.81 | NQO2 (0.66) | P4HBKDM4EMAOAEPHX2XDH | |
| SCHEMBL20802114 | 0.81 | P4HB (0.66) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL811472 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL1697151 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL4227921 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL117644 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL6849807 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL5456136 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH | |
| Quercitrin SCHEMBL3206092 | 0.80 | P4HB (1.00) | P4HBKDM4EMAOAEPHX2XDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150306122-A1 | APP SPECIFIC BACE INHIBITORS (ASBIs) AND USES THEREOF | BUCK INSTITUTE FOR RESEARCH ON AGING | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150306122-A1 | APP SPECIFIC BACE INHIBITORS (ASBIs) AND USES THEREOF | BACE1, APP, GRN | P4HB 2617/4885KDM4E 3559/4885MAOA 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.