Quercitrin

Quercitrin

SCHEMBL4227921

C[C@H]1O[C@@H](Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P4HB P07237 7/20 1.00
KDM4E B2RXH2 6/20 1.00
L3MBTL1 Q9Y468 4/20 1.00
MAOA P21397 4/20 1.00
EPHX2 P34913 4/20 1.00
XDH P47989 4/20 1.00
SLCO2B1 O94956 4/20 1.00
AKR1B1 P15121 3/20 1.00
PIM2 Q9P1W9 2/20 1.00
ALDH1A1 P00352 2/20 1.00
CA12 O43570 2/20 1.00
CA2 P00918 2/20 1.00
CA4 P22748 2/20 1.00
CA7 P43166 2/20 1.00
NQO2 P16083 1/20 0.85
MAPT P10636 5/20 0.84
POLB P06746 4/20 0.84
GAA P10253 4/20 0.84
KDM1A O60341 2/20 0.84
HMGB1 P09429 2/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Quercitrin SCHEMBL29454400 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL117644 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL5456136 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL17628907 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL811472 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL6849807 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL15337986 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL3206092 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL1697151 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2
Quercitrin SCHEMBL29381705 1.00 P4HB (1.00) P4HBKDM4EL3MBTL1MAOAEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090182133-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS SINGAPORE POLYTECHNIC 2009-07-16 US disclosed
EP-1968569-A4 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS SINGAPORE POLYTECHNIC (SG) 2008-12-17 EP disclosed
EP-1968569-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS Singapore Polytechnic (SG) 2008-09-17 EP disclosed
WO-2007075145-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-CORONAVIRAL AGENTS SINGAPORE POLYTECHNIC (SG) 2007-07-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090182133-A1 BENZOPYRANONE DERIVATIVES AND THEIR USE AS ANTI-VIRAL AGENTS SARS1, MAVS, ACE2 P4HB 4070/4885KDM4E 1537/4885L3MBTL1 3336/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.