Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13630750 | 0.87 | NOS1 (0.36) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL21942326 | 0.87 | NOS1 (0.38) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL612802 | 0.87 | NOS1 (0.38) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL611515 | 0.86 | NOS1 (0.37) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL611381 | 0.86 | NOS1 (0.37) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL13862298 | 0.86 | NOS1 (0.39) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL612664 | 0.86 | NOS1 (0.37) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL612059 | 0.85 | RIPK1 (0.37) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL13862294 | 0.84 | RIPK1 (0.39) | PNMTNOS1NOS2RIPK1TAAR1 | |
| SCHEMBL13617220 | 0.83 | RIPK1 (0.38) | PNMTNOS1NOS2RIPK1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164419-A1 | PUPILLOMETRIC ASSESSMENT OF RETINAL PHARMACODYNAMICS AND RESPONSES THEREFROM | ACUCELA INC. (US) | 2015-10-29 | — | — | WO | disclosed |