Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 16/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459688 | 0.84 | FAAH (0.51) | FAAHGPR119 | |
| SCHEMBL14116719 | 0.84 | FAAH (0.51) | FAAHGPR119 | |
| SCHEMBL3179102 | 0.83 | GPR119 (0.51) | FAAHGPR119 | |
| SCHEMBL1103880 | 0.82 | FAAH (0.59) | FAAHGPR119TPSAB1TPSD1TPSG1 | |
| SCHEMBL3170656 | 0.81 | FAAH (0.47) | FAAHGPR119TPSAB1TPSD1TPSG1 | |
| SCHEMBL3170660 | 0.81 | FAAH (0.47) | FAAHGPR119TPSAB1TPSD1TPSG1 | |
| SCHEMBL13531823 | 0.81 | FAAH (0.47) | FAAHGPR119TPSAB1TPSD1TPSG1 | |
| SCHEMBL12356412 | 0.81 | FAAH (0.55) | FAAHGPR119 | |
| SCHEMBL1575630 | 0.81 | FAAH (0.55) | FAAHGPR119 | |
| SCHEMBL1575088 | 0.80 | GPR119 (0.50) | FAAHGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406251-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103334-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |