Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 3/20 | 0.39 |
| ▸ | CHUK | O15111 | 3/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 12/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9935072 | 0.82 | OTUD7B (0.45) | OTUD7BIKBKBCHUKROCK1IRAK4 | |
| SCHEMBL9966451 | 0.80 | OTUD7B (0.43) | OTUD7BIKBKBCHUKIRAK4 | |
| SCHEMBL9966434 | 0.75 | HDAC1 (0.44) | OTUD7BIKBKBCHUKROCK1NPC1 | |
| SCHEMBL19056913 | 0.66 | CNR2 (0.52) | OTUD7BNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL25854530 | 0.65 | NPC1 (0.55) | OTUD7BNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL9966546 | 0.64 | IDO1 (0.46) | LMNA | |
| SCHEMBL12354787 | 0.64 | NTRK1 (0.55) | IKBKBCHUKROCK1NPC1RAB9A | |
| SCHEMBL14325151 | 0.64 | LMNA (0.44) | LMNANPSR1 | |
| SCHEMBL22341606 | 0.63 | NPC1 (0.58) | OTUD7BNPC1RAB9AKMT2AKDM4E | |
| SCHEMBL9966257 | 0.63 | LMNA (0.44) | LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651930-B1 | BIARYLAMIDE INHIBITORS OF LEUKOTRIENE PRODUCTION | BOEHRINGER INGELHEIM INT (DE) | 2015-10-28 | — | — | EP | disclosed |