SCHEMBL1721045

SCHEMBL1721045

O=C(Oc1ccc([N+](=O)[O-])cc1)O[C@H]1CN2CCC1CC2

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
CYP2D6 P10635 3/20 0.46
CYP1A2 P05177 1/20 0.46
CHRNA7 P36544 4/20 0.45
BCHE P06276 1/20 0.45
ACHE P22303 1/20 0.45
GLA P06280 1/20 0.45
CHRM2 P08172 6/20 0.44
CHRM1 P11229 4/20 0.44
CHRM3 P20309 3/20 0.44
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
ALDH1A1 P00352 1/20 0.43
POLB P06746 1/20 0.43
LSS P48449 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1720506 1.00 MEN1 (0.58) MEN1KMT2ACYP2D6CYP1A2CHRNA7
SCHEMBL5649311 0.81 LSS (0.54) MEN1KMT2ACYP2D6CYP1A2CHRNA7
SCHEMBL1724185 0.81 CHRNA7 (0.62) CYP2D6CHRNA7BCHEACHECHRM2
Hydrochloric Acid SCHEMBL9469824 0.80 LSS (0.53) MEN1KMT2ACHRNA7ALDH1A1POLB
SCHEMBL1720624 0.79 LSS (0.46) MEN1KMT2ACYP2D6CHRNA7BCHE
SCHEMBL1721100 0.79 LSS (0.46) MEN1KMT2ACYP2D6CHRNA7BCHE
SCHEMBL1542442 0.78 LSS (0.51) MEN1KMT2ACHRNA7ACHEALDH1A1
SCHEMBL5419769 0.78 LSS (0.51) MEN1KMT2ACHRNA7ACHEALDH1A1
SCHEMBL1542730 0.78 LSS (0.51) MEN1KMT2ACHRNA7ACHEALDH1A1
SCHEMBL5710652 0.78 MEN1 (0.52) MEN1KMT2ACHRNA7ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2406257-B1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA P LTD (IN) 2019-08-07 EP claimed
US-8283470-B2 Method for the preparation of solifenacin and intermediate thereof MEGAFINE PHARMA(P) LTD. (IN) 2012-10-09 US claimed
EP-2406257-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF Megafine Pharma (P) Ltd. (IN) 2012-01-18 EP claimed
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2011-12-29 US claimed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO claimed
CN-119923397-A Improved process for preparing dimethyl-2, 3-dihydro-1H-indene derivatives 柳韩洋行 2025-05-02 CN disclosed
EP-2406257-B1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA P LTD (IN) 2019-08-07 EP disclosed
US-8283470-B2 Method for the preparation of solifenacin and intermediate thereof MEGAFINE PHARMA(P) LTD. (IN) 2012-10-09 US disclosed
US-8283470-B2 Method for the preparation of solifenacin and intermediate thereof MEGAFINE PHARMA(P) LTD. (IN) 2012-10-09 US disclosed
US-8283470-B2 Method for the preparation of solifenacin and intermediate thereof MEGAFINE PHARMA(P) LTD. (IN) 2012-10-09 US disclosed
EP-2406257-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF Megafine Pharma (P) Ltd. (IN) 2012-01-18 EP disclosed
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2011-12-29 US disclosed
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2011-12-29 US disclosed
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2011-12-29 US disclosed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO disclosed
WO-2010103529-A1 A NEW METHOD FOR THE PREPARATION OF SOLIFENACIN AND NEW INTERMEDIATE THEREOF MEGAFINE PHARMA(P) LTD. (IN) 2010-09-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110319621-A1 METHOD FOR THE PREPARATION OF SOLIFENACIN AND INTERMEDIATE THEREOF CHRM3, CHRNA1, ADRA1A MEN1 1973/4885KMT2A 565/4885CYP2D6 612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.