Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 11/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | APLNR | P35414 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17210500 | 1.00 | OPRM1 (0.46) | OPRM1OPRK1CXCR4APLNR | |
| SCHEMBL30471913 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4APLNR | |
| SCHEMBL1247795 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL12899263 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL17210470 | 0.93 | OPRM1 (0.49) | OPRM1OPRK1CXCR4APLNR | |
| SCHEMBL7263725 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL1247799 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL194515 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL21043608 | 0.93 | OPRM1 (0.48) | OPRM1OPRK1CXCR4 | |
| SCHEMBL12261069 | 0.90 | GRB2 (0.50) | OPRM1OPRK1CXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164289-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS | CIDARA THERAPEUTICS, INC. (US) | 2015-10-29 | — | — | WO | disclosed |