SCHEMBL1247799

SCHEMBL1247799

C[C@@H](O)[C@H](N)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 9/20 0.48
OPRK1 P41145 9/20 0.48
GRB2 P62993 1/20 0.46
F2 P00734 1/20 0.45
NRP1 O14786 1/20 0.44
CXCR4 P61073 1/20 0.44
RAMP3 O60896 2/20 0.42
CALCR P30988 2/20 0.42
NTSR2 O95665 1/20 0.42
NTSR1 P30989 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL194515 1.00 OPRM1 (0.48) OPRM1OPRK1GRB2F2NRP1
SCHEMBL21043608 1.00 OPRM1 (0.48) OPRM1OPRK1GRB2F2NRP1
SCHEMBL7263725 1.00 OPRM1 (0.48) OPRM1OPRK1GRB2F2NRP1
SCHEMBL12899263 1.00 OPRM1 (0.48) OPRM1OPRK1GRB2F2NRP1
SCHEMBL1247795 1.00 OPRM1 (0.48) OPRM1OPRK1GRB2F2NRP1
SCHEMBL12261069 0.97 GRB2 (0.50) OPRM1OPRK1GRB2F2NRP1
SCHEMBL13084631 0.97 GRB2 (0.50) OPRM1OPRK1GRB2F2NRP1
SCHEMBL14227389 0.97 GRB2 (0.50) OPRM1OPRK1GRB2F2NRP1
SCHEMBL12899266 0.97 GRB2 (0.50) OPRM1OPRK1GRB2F2NRP1
SCHEMBL12237919 0.97 GRB2 (0.50) OPRM1OPRK1GRB2F2NRP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119331057-A T8 synthetic product and application thereof 海南盛世传恩医疗科技有限公司 2025-01-21 CN claimed
US-20240156960-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT DNARx (US) 2024-05-16 US claimed
CN-115089734-B Carbonized MOFs nanoparticle carrying phagocytic peptide, preparation method and application in imaging and treating retinoblastoma 重庆医科大学附属第二医院 2023-11-03 CN claimed
CN-116615233-A Systems and methods for expressing biomolecules in a subject DNARX公司 2023-08-18 CN claimed
EP-4216935-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT Dnarx (US) 2023-08-02 EP claimed
US-20230212610-A1 NUCLEIC ACID EXPRESSION USING SUBCUTANEOUS ADMINISTRATION DNARx (US) 2023-07-06 US claimed
US-20230172869-A1 A NANO-ENABLED VACCINATION APPROACH FOR CORONAVIRUS DISEASE (COVID-19) AND OTHER VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-06-08 US claimed
EP-4138856-A1 A NANO-ENABLED VACCINATION APPROACH FOR CORONAVIRUS DISEASE (COVID-19) AND OTHER VIRAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-03-01 EP claimed
CN-115089734-A Carbonized MOFs nanoparticles carrying deglutition promoting peptides, preparation method and application in imaging and treating retinoblastoma 重庆医科大学附属第二医院 2022-09-23 CN claimed
WO-2022067091-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT DNARx (US) 2022-03-31 WO claimed
WO-2026089754-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 WO disclosed
WO-2026089752-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES Finitus, LLC (US) 2026-04-30 WO disclosed
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 US disclosed
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES FINITUS LLC (US) 2026-04-23 US disclosed
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates KOSAK KENNETH MICHAEL (US) 2026-04-21 US disclosed
US-4786737-A PREPARATION OF TUFTSIN AND LISINOPRIL AJINOMOTO CO., INC. (JP) 1988-11-22 US disclosed
US-4720554-A Aromatic sulfonic acid salts of a proline derivative AJINOMOTO CO., INC. (JP) 1988-01-19 US disclosed
WO-1987004440-A1 HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS PFIZER INC. (US) 1987-07-30 WO disclosed
EP-0178845-A2 Peptide-substituted heterocyclic immunostimulants PFIZER INC. (US) 1986-04-23 EP disclosed
EP-0157572-A2 Acyltripeptide immunostimulants PFIZER INC. (US) 1985-10-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606830-B2 Protected antibody-drug and aptamer-drug conjugates PABPC1, PABPC4, ABCG2 OPRM1 1611/4885OPRK1 3265/4885GRB2 3257/4885
US-20240156960-A1 SYSTEMS AND METHODS FOR EXPRESSING BIOMOLECULES IN A SUBJECT ACE2, ACE, IGF2BP2 OPRM1 1353/4885OPRK1 1752/4885GRB2 867/4885
US-20260108583-A1 COMPOSITIONS AND METHODS FOR INTRANASAL DELIVERY OF THERAPEUTIC PEPTIDES MUC1, VIP, LGALS4 OPRM1 2580/4885OPRK1 2000/4885GRB2 4117/4885
US-20230212610-A1 NUCLEIC ACID EXPRESSION USING SUBCUTANEOUS ADMINISTRATION FABP4, APMAP, IGF2BP2 OPRM1 1698/4885OPRK1 3997/4885GRB2 1826/4885
US-20260108467-A1 COMPOSITIONS AND METHODS FOR MICROSPHERE DELIVERY OF THERAPEUTIC PEPTIDES FGF23, FIBP, PTMS OPRM1 2774/4885OPRK1 3675/4885GRB2 2589/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.