SCHEMBL17210983

SCHEMBL17210983

CC[C@H]1O[C@@H](c2cn(C)c(=O)n(C)c2=O)C(O)[C@H]1O

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ SLC5A2 P31639 7/20 0.35
▸ TSHR P16473 4/20 0.35
▸ SLC5A1 P13866 2/20 0.35
▸ HTT P42858 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ PNP P00491 1/20 0.33
▸ ADK P55263 2/20 0.32
▸ HSD17B10 Q99714 2/20 0.32
▸ GAA P10253 1/20 0.32
▸ ALOX15 P16050 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14929264 0.89 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL16781795 0.89 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL18573960 0.89 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL14853668 0.89 SLC5A2 (0.44) SLC5A2SLC5A1
SCHEMBL21082362 0.86 SLC5A2 (0.36) SLC5A2TSHRSLC5A1HTTSMN1; SMN2
SCHEMBL17384649 0.85 TSHR (0.36) SLC5A2TSHRSLC5A1HTTSMN1; SMN2
SCHEMBL17211429 0.82 TSHR (0.40) SLC5A2TSHRSLC5A1SMN1; SMN2HSD17B10
SCHEMBL14946151 0.81 FBP1 (0.49) —
SCHEMBL14945996 0.81 SLC5A1 (0.32) SLC5A2TSHRSLC5A1HTTSMN1; SMN2
SCHEMBL15249044 0.81 SLC5A1 (0.32) SLC5A2TSHRSLC5A1HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF MODERNATX, INC. 2015-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150307542-A1 MODIFIED NUCLEIC ACID MOLECULES AND USES THEREOF NSUN2, ADAR, NSUN3 SLC5A2 2756/4885TSHR 2428/4885SLC5A1 2596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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