Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 11/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 10/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.49 |
| ▸ | TSHR | P16473 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 6/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.45 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14727592 | 0.90 | CYP1A2 (0.59) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17212406 | 0.84 | ABCG2 (0.62) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17212422 | 0.82 | CYP2D6 (0.49) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1083778 | 0.82 | CYP2D6 (0.63) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL14474077 | 0.80 | CYP1A2 (0.65) | CYP2D6CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL20273720 | 0.79 | CYP1A2 (0.57) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL1084357 | 0.79 | CYP1A2 (0.56) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL17212408 | 0.78 | CYP2D6 (0.52) | CYP2D6CYP1A2CYP3A4CYP2C19CYP2C9 | |
| SCHEMBL14727627 | 0.77 | GBA1 (0.55) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1083856 | 0.77 | CYP2D6 (0.74) | ABCG2CYP2D6CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | GALENEA CORPORATION | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307477-A1 | THERAPEUTIC COMPOUNDS AND RELATED METHODS OF USE | PPP4C, PTPRG, PPP2CA | ABCG2 3042/4885CYP2D6 4717/4885CYP1A2 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.