Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CD44 | P16070 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16085821 | 0.83 | ALDH1A1 (0.46) | TAAR1TSHRALDH1A1PTGER1PTGER4 | |
| SCHEMBL12426100 | 0.83 | ALDH1A1 (0.46) | TAAR1TSHRALDH1A1PTGER1PTGER4 | |
| SCHEMBL4441030 | 0.82 | TRPA1 (0.37) | TRPA1ATMTSHRALDH1A1PTGER1 | |
| SCHEMBL6546426 | 0.80 | TRPA1 (0.46) | TRPA1ATMTSHRALDH1A1CD44 | |
| SCHEMBL4318496 | 0.80 | TRPA1 (0.46) | TRPA1ATMTSHRALDH1A1CD44 | |
| SCHEMBL10896772 | 0.80 | TRPA1 (0.35) | TRPA1ATMTSHRALDH1A1PTGER1 | |
| SCHEMBL2095465 | 0.80 | ALDH1A1 (0.39) | TRPA1ATMHTR2CTSHRALDH1A1 | |
| SCHEMBL4630319 | 0.80 | TRPA1 (0.35) | TRPA1ATMTSHRALDH1A1PTGER1 | |
| SCHEMBL2095468 | 0.80 | ALDH1A1 (0.39) | TRPA1ATMHTR2CTSHRALDH1A1 | |
| SCHEMBL27994690 | 0.80 | TRPA1 (0.40) | TRPA1ATMTSHRALDH1A1PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546174-B2 | Inhibitor of apoptosis protein (IAP) antagonists | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2017-01-17 | — | — | US | disclosed |
| US-20150307499-A1 | INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE | 2015-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150307499-A1 | INHIBITOR OF APOPTOSIS PROTEIN (IAP) ANTAGONISTS | API5, XIAP, BIRC5 | TAAR1 4428/4885TRPA1 3617/4885ATM 1783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.