Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17213335 | 0.81 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL14949130 | 0.75 | — | — | |
| SCHEMBL27352017 | 0.69 | DGAT1 (0.37) | DGAT1 | |
| SCHEMBL27609135 | 0.69 | — | — | |
| SCHEMBL15139 | 0.67 | — | — | |
| SCHEMBL4328011 | 0.67 | — | — | |
| SCHEMBL28083205 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL13717027 | 0.65 | — | — | |
| Iodide SCHEMBL9839224 | 0.65 | — | — | |
| Phosphine SCHEMBL27995477 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015164573-A1 | PURINE DERIVATIVES AS CD73 INHIBITORS FOR THE TREATMENT OF CANCER | VITAE PHARMACEUTICALS, INC. (US) | 2015-10-29 | — | — | WO | disclosed |