Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28325018 | 0.74 | DGAT1 (0.44) | DGAT1 | |
| SCHEMBL27354793 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL27977690 | 0.72 | MEN1 (0.40) | — | |
| SCHEMBL17213480 | 0.69 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL27977694 | 0.69 | HCAR2 (0.36) | ALDH1A1 | |
| SCHEMBL1527282 | 0.67 | — | — | |
| Ammonia Solution, Strong SCHEMBL7639328 | 0.67 | DGAT1 (0.70) | DGAT1KCNN4ALDH1A1SRC | |
| Ammonia Solution, Strong SCHEMBL243818 | 0.67 | — | — | |
| SCHEMBL8096308 | 0.65 | DGAT1 (0.46) | DGAT1KCNN4ALDH1A1SRC | |
| SCHEMBL4672716 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110066273-A | A kind of single arylpyrimidines HIV-1 reverse transcriptase inhibitor of the ring containing triazole and the preparation method and application thereof | 山东大学 | 2019-07-30 | — | — | CN | claimed |
| CN-110483220-A | A kind of NEW TYPE OF COMPOSITE solid propellant and preparation method thereof and processing method | BEIJING INSTITUTE TECH | 2019-11-22 | — | — | CN | disclosed |
| CN-110483665-A | A kind of preparation method of end triazolyl polybutadiene | BEIJING INSTITUTE TECH | 2019-11-22 | — | — | CN | disclosed |
| CN-110066273-A | A kind of single arylpyrimidines HIV-1 reverse transcriptase inhibitor of the ring containing triazole and the preparation method and application thereof | 山东大学 | 2019-07-30 | — | — | CN | disclosed |
| CN-109641911-A | Seco- cyclopropyl pyrrolo-indole compound and its antibody-drug conjugates and preparation and application | 百时美施贵宝公司 | 2019-04-16 | — | — | CN | disclosed |
| CN-109369623-A | 1,2,3 triazole diaryl pyrimidine derivatives of a kind of substitution and the preparation method and application thereof | 山东大学 | 2019-02-22 | — | — | CN | disclosed |
| CN-109153643-A | Substituted indole MCL-1 inhibitors | 范德比尔特大学 | 2019-01-04 | — | — | CN | disclosed |
| CN-105992766-A | Pyrrolo [3,2-C ] pyridine derivatives as TLR inhibitors | 武田药品工业株式会社 | 2016-10-05 | — | — | CN | disclosed |
| CN-104003983-B | Containing the substituted bis-heterocyclic compounds of phenylseleno and preparation and application thereof | 浙江工业大学 | 2016-08-17 | — | — | CN | disclosed |
| CN-105682655-A | Antimicrobial compounds | 阿克塞利亚制药公司 | 2016-06-15 | — | — | CN | disclosed |
| CN-1167681-C | Condensed indoline derivatives and their use as 5HT, in particular 5HT2C receptor ligands | О | 2004-09-22 | — | — | CN | disclosed |
| CN-1134440-C | 4-oxo-3,5-dihydro-4H-pyridazino [4,5-b]-indole-1-acetamide derivatives, their prepn. and their application in therapy | �����ʩ���عɷݹ�˾ | 2004-01-14 | — | — | CN | disclosed |
| CN-1395565-A | Indole derivatives as MCP-1 receptor antagonists | ASTRAZENECA AB (SE) | 2003-02-05 | — | — | CN | disclosed |
| CN-1379761-A | Fused indoline derivatives and their use as 5HT, in particular 5HT2C, receptor ligands | VERNALIS RESAERCH LTD (GB) | 2002-11-13 | — | — | CN | disclosed |
| CN-1351591-A | Anti-inflammatory indole derivatives | ASTRAZENECA AB (SE) | 2002-05-29 | — | — | CN | disclosed |
| CN-1077572-C | Substituted bisindolylmaleimides for inhibition of cell proliferation | HOFFMANN LA ROCHE (CH) | 2002-01-09 | — | — | CN | disclosed |
| CN-1061341-C | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 2001-01-31 | — | — | CN | disclosed |
| CN-1265108-A | 4-oxo-3,5-dihydro-4H-pyridazino [4,5-b]-indole-1-acetamide derivatives, their prepn. and their application in therapy | SANOFI SYNTHELABO (FR) | 2000-08-30 | — | — | CN | disclosed |
| CN-1226249-A | Substituted bisindolylmaleimides for inhibition of cell proliferation | HOFFMANN LA ROCHE (CH) | 1999-08-18 | — | — | CN | disclosed |
| CN-1105988-A | 1-amino-ethylindole-derivatives | HOFFMANN LA ROCHE (CH) | 1995-08-02 | — | — | CN | disclosed |