Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 2/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30092232 | 0.81 | P2RX7 (0.31) | P2RX7IDH1 | |
| SCHEMBL9928616 | 0.81 | P2RX7 (0.38) | CBLBP2RX7IDH1 | |
| SCHEMBL29552743 | 0.78 | KDM4E (0.34) | CBLB | |
| SCHEMBL30305706 | 0.78 | P2RX7 (0.36) | CBLBP2RX7 | |
| SCHEMBL26675086 | 0.78 | KDM4E (0.34) | CBLB | |
| SCHEMBL26981246 | 0.76 | KDM4E (0.37) | CBLB | |
| SCHEMBL29947388 | 0.76 | KDM4E (0.37) | CBLB | |
| SCHEMBL1578654 | 0.74 | KDM4E (0.41) | CBLBP2RX7 | |
| SCHEMBL3291771 | 0.73 | IDH1 (0.39) | IDH1 | |
| SCHEMBL15542377 | 0.73 | KMT2A (0.44) | CBLBP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426135-A1 | UREA DERIVATIVE HAVING PI3K INHIBITORY ACTIVITY | Shionogi&Co., Ltd. (JP) | 2012-03-07 | — | — | EP | disclosed |