Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 2/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19997390 | 0.90 | TMPRSS2 (0.39) | TMPRSS2ADORA3 | |
| SCHEMBL14681868 | 0.89 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL30363053 | 0.88 | TMPRSS2 (0.49) | TMPRSS2ADKADORA3CDK5CDK5R1 | |
| SCHEMBL16519861 | 0.84 | TMPRSS2 (0.49) | TMPRSS2ADKPRMT5WDR77 | |
| SCHEMBL16519895 | 0.82 | PRMT5 (0.34) | ADKPRMT5WDR77 | |
| SCHEMBL30363078 | 0.76 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL27121074 | 0.74 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL14681870 | 0.74 | TMPRSS2 (0.47) | TMPRSS2 | |
| SCHEMBL25379160 | 0.74 | TMPRSS2 (0.51) | TMPRSS2 | |
| SCHEMBL25432619 | 0.74 | TMPRSS2 (0.51) | TMPRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2937350-A1 | 1' -substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2015-10-28 | — | — | EP | disclosed |