Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | HSPA8 | P11142 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30363078 | 0.88 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL17215154 | 0.88 | TMPRSS2 (0.40) | TMPRSS2CDK5CDK5R1ADORA3ADK | |
| SCHEMBL19997390 | 0.86 | TMPRSS2 (0.39) | TMPRSS2ADORA3POLB | |
| SCHEMBL14681868 | 0.85 | TMPRSS2 (0.38) | TMPRSS2 | |
| Gs-441524 SCHEMBL24667691 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A | |
| Gs-441524 SCHEMBL15998246 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A | |
| Gs-441524 SCHEMBL23870459 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A | |
| Gs-441524 SCHEMBL22663744 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A | |
| Gs-441524 SCHEMBL10120691 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A | |
| Gs-441524 SCHEMBL10120689 | 0.83 | TMPRSS2 (0.60) | TMPRSS2CDK5CDK5R1HSPA8ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292565-B | Nucleoside compound and preparation method and application thereof | 浙江森科建设有限公司 | 2023-01-31 | — | — | CN | disclosed |