Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17215154 | 0.90 | TMPRSS2 (0.40) | TMPRSS2ADORA3 | |
| SCHEMBL14681868 | 0.88 | TMPRSS2 (0.38) | TMPRSS2 | |
| SCHEMBL30363053 | 0.86 | TMPRSS2 (0.49) | TMPRSS2ADORA3POLB | |
| SCHEMBL19997424 | 0.83 | ADORA3 (0.31) | ADORA3KDM4EPOLBHTTRECQL | |
| SCHEMBL15607071 | 0.77 | — | — | |
| SCHEMBL16519861 | 0.74 | TMPRSS2 (0.49) | TMPRSS2 | |
| SCHEMBL30363078 | 0.74 | TMPRSS2 (0.48) | TMPRSS2 | |
| SCHEMBL25433905 | 0.73 | TMPRSS2 (0.48) | TMPRSS2KDM4EPOLBHTTRECQL | |
| SCHEMBL25383499 | 0.73 | TMPRSS2 (0.48) | TMPRSS2KDM4EPOLBHTTRECQL | |
| SCHEMBL16519895 | 0.73 | PRMT5 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE46762-E1 | 1′-substituted carba-nucleoside analogs for antiviral treatment | GILEAD SCIENCES, INC (US) | 2018-03-27 | — | — | US | disclosed |