SCHEMBL17216136

SCHEMBL17216136

C=Cc1ccccc1CON=CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.33
TSHR P16473 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CYP2C19 P33261 1/20 0.31
USP2 O75604 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17217289 0.79 KMT2A (0.36) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL17218275 0.79 BACE1 (0.34) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL17218729 0.79 TAAR1 (0.40) KMT2ALMNA
SCHEMBL17216131 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17216134 0.78 ALDH1A1 (0.32) ALDH1A1
SCHEMBL17217470 0.78 KMT2A (0.48) HPGDKMT2AALDH1A1NPC1RAB9A
SCHEMBL17217936 0.78 IDO1 (0.46) KMT2AMEN1ALDH1A1USP2LMNA
SCHEMBL17217464 0.77 KMT2A (0.37) KMT2AMEN1ALDH1A1NPC1RAB9A
SCHEMBL17218548 0.76 IDO1 (0.50) HPGDKMT2AMEN1ALDH1A1NPC1
SCHEMBL17218424 0.75 KMT2A (0.30) KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2940012-B1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL CO (JP) 2019-01-30 EP disclosed
US-9560850-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-07 US disclosed
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-26 US disclosed
EP-2940012-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF Sumitomo Chemical Company Limited (JP) 2015-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF RTN3, CYP51A1, TCOF1 HPGD 4830/4885TSHR 19/4885MAPK1 1283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.