SCHEMBL17216166

SCHEMBL17216166

CC/[C]=N\OCc1ccc(F)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.44
AGXT P21549 2/20 0.44
MAOB P27338 7/20 0.41
APP P05067 1/20 0.37
MIF P14174 1/20 0.36
LMNA P02545 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.34
LOXL2 Q9Y4K0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17216169 1.00 IDO1 (0.44) IDO1AGXTMAOBAPPMIF
SCHEMBL17218903 0.86 IDO1 (0.41) IDO1AGXTMAOBAPPMIF
SCHEMBL17218906 0.86 IDO1 (0.41) IDO1AGXTMAOBAPPMIF
SCHEMBL17986276 0.85 IDO1 (0.47) IDO1AGXTMAOBAPPMIF
SCHEMBL17218693 0.85 CYP2A6 (0.38) IDO1AGXTL3MBTL1TDP1KMT2A
SCHEMBL17986275 0.85 IDO1 (0.47) IDO1AGXTMAOBAPPMIF
SCHEMBL17218691 0.85 CYP2A6 (0.38) IDO1AGXTL3MBTL1TDP1KMT2A
SCHEMBL17216964 0.83 AGXT (0.45) IDO1AGXTMAOBL3MBTL1POLB
SCHEMBL17216967 0.83 AGXT (0.45) IDO1AGXTMAOBL3MBTL1POLB
SCHEMBL17219271 0.83 PSMD14 (0.40) IDO1AGXTMAOBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2940012-B1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF SUMITOMO CHEMICAL CO (JP) 2019-01-30 EP disclosed
US-9635857-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-05-02 US disclosed
US-9560850-B2 Tetrazolinone compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-02-07 US disclosed
US-20160235065-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-18 US disclosed
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-26 US disclosed
EP-2940012-A1 TETRAZOLINONE COMPOUND AND APPLICATIONS THEREOF Sumitomo Chemical Company Limited (JP) 2015-11-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160235065-A1 TETRAZOLINONE COMPOUND AND USE THEREOF MRPS17, TAOK1, TAOK3 IDO1 1822/4885AGXT 335/4885MAOB 2207/4885
US-20150336908-A1 TETRAZOLINONE COMPOUND AND USE THEREOF RTN3, CYP51A1, TCOF1 IDO1 2882/4885AGXT 1423/4885MAOB 3611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.