Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1721055 | 0.83 | ADORA1 (0.43) | ALDH1A1L3MBTL1 | |
| SCHEMBL30924465 | 0.81 | MEN1 (0.35) | LMNATSHRALDH1A1L3MBTL1HRH3 | |
| SCHEMBL598302 | 0.78 | ALDH1A1 (0.34) | LMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10619024 | 0.77 | MEN1 (0.51) | CYP4F2CYP4A11LMNAALDH1A1L3MBTL1 | |
| SCHEMBL21840081 | 0.77 | ALDH1A1 (0.36) | LMNATSHRALDH1A1L3MBTL1HRH3 | |
| SCHEMBL23852946 | 0.77 | MAPT (0.35) | LMNATSHRALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16836169 | 0.77 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL23664480 | 0.73 | ALDH1A1 (0.46) | CYP4F2CYP4A11LMNATSHRALDH1A1 | |
| SCHEMBL8117386 | 0.73 | MAPT (0.43) | LMNATSHRPOLBALDH1A1GAA | |
| SCHEMBL3988008 | 0.72 | ALDH1A1 (0.51) | CYP4F2CYP4A11LMNATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406251-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | Prosidion Limited (GB) | 2012-01-18 | — | — | EP | disclosed |
| WO-2010103334-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2010-09-16 | — | — | WO | disclosed |