Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795933 | 0.88 | TSHR (0.46) | TSHRLMNARAB9AMAPTGAA | |
| SCHEMBL17220066 | 0.85 | RAB9A (0.51) | TSHRRAB9AMAPTGAANPC1 | |
| SCHEMBL17220341 | 0.82 | LMNA (0.43) | TSHRLMNARAB9AMAPTGAA | |
| SCHEMBL17220221 | 0.81 | TSHR (0.53) | TSHRLMNARAB9AMAPTNPC1 | |
| SCHEMBL796782 | 0.79 | LMNA (0.40) | TSHRLMNARAB9AMAPTGAA | |
| SCHEMBL796781 | 0.79 | LMNA (0.40) | TSHRLMNARAB9AMAPTGAA | |
| SCHEMBL796783 | 0.79 | LMNA (0.40) | TSHRLMNARAB9AMAPTGAA | |
| Dyrene SCHEMBL2938800 | 0.78 | TSHR (0.83) | TSHRLMNARAB9AMAPTNPC1 | |
| SCHEMBL11802348 | 0.77 | MAPT (0.68) | TSHRLMNARAB9AMAPTNPC1 | |
| SCHEMBL14869761 | 0.75 | TSHR (0.67) | TSHRLMNARAB9AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |