Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 15/20 | 0.60 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL180868 | 0.81 | DGAT1 (0.60) | DGAT1KMT2A | |
| SCHEMBL180932 | 0.81 | DGAT1 (0.60) | DGAT1KMT2A | |
| SCHEMBL180931 | 0.81 | DGAT1 (0.60) | DGAT1KMT2A | |
| SCHEMBL180532 | 0.80 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL180533 | 0.80 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL180531 | 0.80 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL1447834 | 0.78 | DGAT1 (0.68) | DGAT1CAMK2D | |
| SCHEMBL180651 | 0.78 | DGAT1 (0.68) | DGAT1CAMK2D | |
| SCHEMBL4890892 | 0.77 | DGAT1 (0.96) | DGAT1KMT2AMEN1 | |
| SCHEMBL182564 | 0.76 | DGAT1 (0.52) | DGAT1CAMK2DKMT2AMEN1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404905-A1 | New compounds | Novartis AG (CH) | 2012-01-11 | — | — | EP | disclosed |