SCHEMBL172201

SCHEMBL172201

C=CC(=O)Oc1ccc(N(c2ccc(C)cc2)c2cccc(OC(=O)C=C)c2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
ALDH1A1 P00352 2/20 0.42
LMNA P02545 3/20 0.39
HSD17B1 P14061 2/20 0.39
HSD17B2 P37059 2/20 0.39
BCHE P06276 1/20 0.36
ACHE P22303 1/20 0.36
KMT2A Q03164 1/20 0.36
MTNR1A P48039 1/20 0.36
MTNR1B P49286 1/20 0.36
TGM2 P21980 1/20 0.36
MAPT P10636 3/20 0.35
NR1I2 O75469 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
MAPK1 P28482 1/20 0.35
CYP2C19 P33261 1/20 0.35
HTR2B P41595 1/20 0.35
CYP51A1 Q16850 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12234135 0.97 LMNA (0.41) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL9915690 0.97 LMNA (0.41) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL14195432 0.96 THRB (0.42) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL172502 0.96 THRB (0.42) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL9915674 0.95 BCHE (0.42) THRBALDH1A1LMNABCHEACHE
SCHEMBL10102832 0.94 THRB (0.47) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL172547 0.94 MAPT (0.41) THRBALDH1A1BCHEACHEMAPT
SCHEMBL12234168 0.93 MAPT (0.41) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL13777465 0.93 MAPT (0.41) THRBALDH1A1LMNAHSD17B1HSD17B2
SCHEMBL12234121 0.93 LMNA (0.44) THRBALDH1A1LMNAHSD17B1HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 EP disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 US disclosed
US-7659044-B2 Photoconductor, producing method thereof, image forming process and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-7659044-B2 Photoconductor, producing method thereof, image forming process and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2010-02-09 US disclosed
US-7629103-B2 Photoconductor, manufacturing method thereof, image forming process and image forming apparatus using photoconductor, and process cartridge RICOH COMPANY, LTD. (JP) 2009-12-08 US disclosed
US-20090185821-A1 Electrophotographic photoreceptor, and image formihg appratus and process cartridge using same RICOH COMPANY, LTD (JP) 2009-07-23 US disclosed
US-20090162763-A1 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-06-25 US disclosed
US-20090162763-A1 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. 2009-06-25 US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 EP disclosed