Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220109 | 1.00 | SIGMAR1 (0.42) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL796185 | 0.86 | KDM4E (0.44) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL24214192 | 0.86 | KDM4E (0.44) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL15477239 | 0.86 | KDM4E (0.44) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL25933662 | 0.79 | SIGMAR1 (0.47) | SIGMAR1DRD2FUCA1KDM4EALDH1A1 | |
| SCHEMBL17220186 | 0.77 | SIGMAR1 (0.52) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL17220185 | 0.77 | SIGMAR1 (0.52) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL5796114 | 0.75 | HRH3 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL5793105 | 0.75 | HRH3 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B | |
| SCHEMBL5793108 | 0.75 | HRH3 (0.58) | SIGMAR1DRD2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |