Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 4/20 | 0.52 |
| ▸ | HTR2B | P41595 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220185 | 1.00 | SIGMAR1 (0.52) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL24214192 | 0.79 | KDM4E (0.44) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL15477239 | 0.79 | KDM4E (0.44) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL796185 | 0.79 | KDM4E (0.44) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL17220060 | 0.78 | S1PR5 (0.49) | FUCA1 | |
| SCHEMBL17220061 | 0.78 | S1PR5 (0.49) | FUCA1 | |
| SCHEMBL17220126 | 0.78 | BCHE (0.44) | DRD2FUCA1 | |
| SCHEMBL17220125 | 0.78 | BCHE (0.44) | DRD2FUCA1 | |
| SCHEMBL17220110 | 0.77 | SIGMAR1 (0.42) | SIGMAR1HTR2AHTR2CHTR2BDRD2 | |
| SCHEMBL17220109 | 0.77 | SIGMAR1 (0.42) | SIGMAR1HTR2AHTR2CHTR2BDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |