Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DHFR | P00374 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795288 | 0.82 | TSHR (0.48) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL796712 | 0.82 | TSHR (0.48) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL8608925 | 0.79 | DHFR (0.45) | TSHRTP53DHFRMAPTLMNA | |
| SCHEMBL17220453 | 0.79 | TSHR (0.48) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL17220115 | 0.78 | DHFR (0.44) | TSHRDHFRMAPTLMNASMN1; SMN2 | |
| SCHEMBL7700052 | 0.75 | DHFR (0.51) | TSHRDHFRMAPTLMNASMN1; SMN2 | |
| SCHEMBL795662 | 0.74 | TSHR (0.41) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL17220137 | 0.74 | TSHR (0.41) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL17220070 | 0.74 | SMN1; SMN2 (0.45) | TSHRTP53ALOX15DHFRMAPT | |
| SCHEMBL17220364 | 0.73 | TSHR (0.45) | TSHRTP53ALOX15DHFRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |