Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | DHFR | P00374 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | CRHBP | P24387 | 1/20 | 0.30 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL795662 | 1.00 | TSHR (0.41) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL17220453 | 0.84 | TSHR (0.48) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL795663 | 0.81 | MAPT (0.35) | MAPTDHFRNPC1JAK2RAB9A | |
| SCHEMBL17220160 | 0.78 | DHFR (0.41) | TSHRMAPTDHFRNPC1JAK2 | |
| SCHEMBL17220364 | 0.78 | TSHR (0.45) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL795288 | 0.77 | TSHR (0.48) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL796712 | 0.77 | TSHR (0.48) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL796138 | 0.75 | MAPT (0.59) | TSHRMAPTDHFRNPC1JAK2 | |
| SCHEMBL17220116 | 0.74 | TSHR (0.45) | TSHRTP53ALOX15MAPTDHFR | |
| SCHEMBL17220376 | 0.72 | MTNR1A (0.39) | TSHRTP53ALOX15DHFRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |