Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 6/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17220458 | 0.83 | MAPT (0.52) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL796421 | 0.80 | PDE4A (0.35) | DHFR | |
| SCHEMBL17220005 | 0.79 | TSHR (0.54) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL17220379 | 0.79 | MAPT (0.55) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL17220093 | 0.78 | MAPT (0.52) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL796039 | 0.77 | MAPT (0.72) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL17220082 | 0.76 | LMNA (0.50) | MAPTTSHRLMNASMN1; SMN2DHFR | |
| SCHEMBL795723 | 0.75 | MAPT (0.56) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL17220123 | 0.74 | MAPT (0.55) | MAPTTSHRLMNASMN1; SMN2CRHBP | |
| SCHEMBL796535 | 0.74 | MAPT (0.48) | MAPTTSHRLMNASMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616465-B1 | TRIAZINE-OXADIAZOLES | NOVARTIS AG (CH) | 2015-11-04 | — | — | EP | disclosed |