Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA6 | P23280 | 3/20 | 0.36 |
| ▸ | CA7 | P43166 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA5A | P35218 | 2/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylenediamine SCHEMBL1436759 | 0.86 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL2170654 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2169963 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2168930 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL9744398 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL8366402 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL1524112 | 0.86 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL6698389 | 0.86 | NFKB1 (0.40) | NFKB1TSHRALDH1A1CA12CA6 | |
| Ethylenediamine SCHEMBL10537063 | 0.86 | — | — | |
| Ethylenediamine SCHEMBL2171867 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11702437-B2 | Method for producing aqueous preparations of complexes of platinum group metals | UMICORE AG & CO. KG (DE) | 2023-07-18 | — | — | US | disclosed |
| US-9856280-B2 | Method for producing aqueous preparations of complexes of platinum group metals | UMICORE AG & CO., KG (DE) | 2018-01-02 | — | — | US | disclosed |
| US-20150315224-A1 | METHOD FOR PRODUCING AQUEOUS PREPARATIONS OF COMPLEXES OF PLATINUM GROUP METALS | UMICORE AG & CO. KG (DE) | 2015-11-05 | — | — | US | disclosed |