Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.61 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BCL2A1 | Q16548 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12755201 | 0.92 | THRB (0.54) | THRBELANEALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11987133 | 0.89 | THRB (0.71) | THRBBCL2A1THRAMEN1KMT2A | |
| SCHEMBL7214462 | 0.88 | THRB (0.80) | THRBELANEALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL13777593 | 0.88 | THRB (0.50) | THRBALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL12755176 | 0.86 | THRB (0.46) | THRBALDH1A1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL9915749 | 0.85 | THRB (0.66) | THRBSMN1; SMN2BCL2A1THRAKMT2A | |
| SCHEMBL9915814 | 0.85 | THRB (0.66) | THRBSMN1; SMN2BCL2A1THRAKMT2A | |
| SCHEMBL22605051 | 0.85 | THRB (0.85) | THRBALDH1A1SMN1; SMN2BCL2A1RAB9A | |
| SCHEMBL12934710 | 0.84 | THRB (0.64) | THRBELANESMN1; SMN2BCL2A1RAB9A | |
| SCHEMBL10102840 | 0.83 | THRB (0.63) | THRBALDH1A1SMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847881-B1 | Image forming apparatus, image forming method, and process cartridge | RICOH CO LTD (JP) | 2012-03-07 | — | — | EP | disclosed |