Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487244 | 0.93 | RBP4 (0.81) | RBP4 | |
| SCHEMBL17222853 | 0.92 | RBP4 (1.00) | RBP4 | |
| SCHEMBL29598255 | 0.90 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17222910 | 0.90 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17229902 | 0.90 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17229643 | 0.89 | RBP4 (0.82) | RBP4 | |
| SCHEMBL17229640 | 0.89 | RBP4 (0.85) | RBP4 | |
| SCHEMBL17222948 | 0.88 | RBP4 (0.85) | RBP4 | |
| SCHEMBL29597086 | 0.88 | RBP4 (0.85) | RBP4 | |
| SCHEMBL17229900 | 0.87 | RBP4 (1.00) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111393434-B | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2022-11-04 | — | — | CN | disclosed |
| CN-111393434-A | Substituted 4-phenylpiperidines, their preparation and use | 哥伦比亚大学董事会 | 2020-07-10 | — | — | CN | disclosed |
| EP-3137168-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARAITON AND USE | The Trustees of Columbia University in the City of New York (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015168286-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARAITON AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-05 | — | — | WO | disclosed |