Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17222883 | 0.93 | RBP4 (0.88) | RBP4 | |
| SCHEMBL17222853 | 0.91 | RBP4 (1.00) | RBP4 | |
| SCHEMBL29598255 | 0.90 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17222910 | 0.90 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17224449 | 0.90 | RBP4 (0.85) | RBP4 | |
| SCHEMBL17229627 | 0.88 | RBP4 (1.00) | RBP4 | |
| SCHEMBL17229643 | 0.88 | RBP4 (0.82) | RBP4 | |
| SCHEMBL25438914 | 0.88 | RBP4 (0.77) | RBP4 | |
| SCHEMBL24727633 | 0.87 | RBP4 (0.78) | RBP4 | |
| SCHEMBL24157921 | 0.87 | RBP4 (0.94) | RBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250241902-A1 | METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION | BELITE BIO INC (US) | 2025-07-31 | — | — | US | disclosed |
| US-12364693-B2 | Methods of treating metabolic diseases with fused bicyclic pyrazoles | BELITE BIO, INC (US) | 2025-07-22 | — | — | US | disclosed |
| EP-4507566-A1 | METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION | Belite Bio, Inc (US) | 2025-02-19 | — | — | EP | disclosed |
| US-20250041227-A1 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | BELITE BIO INC (US) | 2025-02-06 | — | — | US | disclosed |
| EP-4436577-A1 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | Belite Bio, Inc (US) | 2024-10-02 | — | — | EP | disclosed |
| CN-118574615-A | Tablet formulations of RBP4 inhibitors and methods of use | 倍亮生物有限公司 | 2024-08-30 | — | — | CN | disclosed |
| US-20240248099-A1 | BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION | BELITE BIO, LLC | 2024-07-25 | — | — | US | disclosed |
| US-11951100-B2 | Formulations of RBP4 inhibitors and methods of use | BELITE BIO, LLC (US) | 2024-04-09 | — | — | US | disclosed |
| EP-4340701-A1 | BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION | Belite Bio, LLC (US) | 2024-03-27 | — | — | EP | disclosed |
| CN-117440774-A | Biomarkers of age-related macular degeneration | 倍亮生物有限责任公司 | 2024-01-23 | — | — | CN | disclosed |
| US-20180030060-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2018-02-01 | — | — | US | disclosed |
| US-9777010-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-10-03 | — | — | US | disclosed |
| US-9777010-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160368925-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-22 | — | — | US | disclosed |
| US-20160368925-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-12-22 | — | — | US | disclosed |
| US-9434727-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-09-06 | — | — | US | disclosed |
| US-9434727-B2 | Substituted 4-phenylpiperidines, their preparation and use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2016-09-06 | — | — | US | disclosed |
| US-20150315197-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-05 | — | — | US | disclosed |
| US-20150315197-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-05 | — | — | US | disclosed |
| WO-2015168286-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARAITON AND USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150315197-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | RBP4 1884/4885 |
| US-20250241902-A1 | METHODS, COMPOSITIONS AND SYSTEMS FOR EVALUATION OF VISUAL FUNCTION | PDE6C, SERPINA6, PDE6H | RBP4 11/4885 |
| US-20160368925-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | RBP4 1950/4885 |
| US-12364693-B2 | Methods of treating metabolic diseases with fused bicyclic pyrazoles | RBP4, RBP1, FABP4 | RBP4 1/4885 |
| US-20240248099-A1 | BIOMARKERS FOR AGE-RELATED MACULAR DEGENERATION | AGER, RBP4, RBP1 | RBP4 2/4885 |
| US-20250041227-A1 | TABLET FORMULATIONS OF RBP4 INHIBITORS AND METHODS OF USE | RBP4, RBP1, RBM3 | RBP4 1/4885 |
| US-20180030060-A1 | SUBSTITUTED 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | HRH4, HRH3, HRH2 | RBP4 1884/4885 |
| US-11951100-B2 | Formulations of RBP4 inhibitors and methods of use | RBP4, RBP1, RBM3 | RBP4 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.