Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.68 |
| ▸ | RELA | Q04206 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 4/20 | 0.55 |
| ▸ | PLAU | P00749 | 3/20 | 0.55 |
| ▸ | ELANE | P08246 | 3/20 | 0.55 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.55 |
| ▸ | SCN4A | P35499 | 2/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22341331 | 0.83 | SCN4A (0.55) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL14027526 | 0.81 | SCN4A (0.57) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL27795462 | 0.80 | SCN4A (0.74) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL28553729 | 0.79 | SMN1; SMN2 (0.47) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL28861208 | 0.76 | PLAU (0.62) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL2181609 | 0.76 | SCN4A (0.62) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL22492988 | 0.76 | KMT2A (0.53) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL1224671 | 0.75 | RAB9A (0.54) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL427240 | 0.75 | SMN1; SMN2 (0.68) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E | |
| SCHEMBL20954002 | 0.74 | KMT2A (0.50) | KMT2ASMN1; SMN2RAB9AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167262-B2 | Herbicidal substituted 3-arylpyrazoles | FMC CORPORATION (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170183312-A1 | HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES | FMC CORPORATION | 2017-06-29 | — | — | US | disclosed |
| WO-2015191377-A1 | HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-12-17 | — | — | WO | disclosed |
| WO-2015167795-A1 | HERBICIDAL SUBSTITUTED 3-PHENYL-4-FLUOROBENZOYL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-05 | — | — | WO | disclosed |
| CN-1165482-A | Pyrazole pharmaceutical compositions as protein kinase inhibitors | COR THERAPEUTICS INC (US) | 1997-11-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170183312-A1 | HERBICIDAL SUBSTITUTED 3-ARYLPYRAZOLES | CYP1B1, CYP1A1, TYR | KMT2A 3503/4885SMN1; SMN2 4542/4885RAB9A 3076/4885 |
| US-10167262-B2 | Herbicidal substituted 3-arylpyrazoles | CYP1B1, CYP1A1, TYR | KMT2A 3503/4885SMN1; SMN2 4542/4885RAB9A 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.