Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLAU | P00749 | 2/20 | 0.45 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20979545 | 0.77 | MAPT (0.37) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL15772468 | 0.77 | MAPT (0.56) | SMN1; SMN2KDM4EMAOBMAPTLMNA | |
| SCHEMBL16348315 | 0.75 | MAPT (0.45) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL17224648 | 0.74 | KMT2A (0.68) | KMT2ATDP1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL16348304 | 0.73 | CACNA1G (0.45) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL366947 | 0.72 | IDO1 (0.50) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL1224671 | 0.69 | RAB9A (0.54) | KMT2ATDP1L3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL2403689 | 0.68 | KDM4C (0.69) | KDM4ECYP19A1 | |
| SCHEMBL13523181 | 0.68 | IDO1 (0.44) | KMT2AHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5990815 | 0.67 | CYP19A1 (0.56) | KMT2AHPGDSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010915-B1 | SUBSTITUTED (3-(5-CHLORO-2-HYDROXYPHENYL)-1-BENZOYL-1H-PYRAZOLE COMPOUNDS AS HISTONE DEMETHYLASE INHIBITORS | UNIV UTAH RES FOUND (US) | 2019-05-08 | — | — | EP | disclosed |