Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 7/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.47 |
| ▸ | RARB | P10826 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.43 |
| ▸ | RARG | P13631 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | UTRN | P46939 | 1/20 | 0.40 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29819601 | 0.81 | PSMB5 (0.51) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL28831076 | 0.81 | PSMB5 (0.51) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL29394557 | 0.79 | TTR (0.52) | ESR1ESR2EIF4A1KDM4EMEN1 | |
| SCHEMBL28267364 | 0.78 | PSMB5 (0.56) | KDM4EMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL16215311 | 0.76 | NPC1 (0.64) | ESR1ESR2HDAC6KDM4EMEN1 | |
| SCHEMBL9001595 | 0.76 | KDM4E (0.59) | ESR1ESR2KDM4EMEN1NPC1 | |
| SCHEMBL8303921 | 0.75 | NPC1 (0.52) | ESR1ESR2HDAC6TLR8UTRN | |
| SCHEMBL3163456 | 0.74 | RARB (0.52) | RARBRARARARGTLR8GCGR | |
| SCHEMBL8302089 | 0.74 | ESR1 (0.44) | ESR1ESR2RARBRARARARG | |
| SCHEMBL24205728 | 0.74 | NPC1 (0.52) | KDM4EMEN1NPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9175220-B2 | High scattering smectic liquid crystal material and display device using the same | HALATION PHOTONICS CORPORATION (CN) | 2015-11-03 | — | — | US | disclosed |