Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.52 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 1/20 | 0.52 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.52 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.52 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.42 |
| ▸ | ESR1 | P03372 | 4/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.42 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28903550 | 0.86 | TTR (0.57) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL28267364 | 0.84 | PSMB5 (0.56) | GPR119MEN1KMT2APSMB5KDM4E | |
| SCHEMBL28831076 | 0.79 | PSMB5 (0.51) | GPR119MEN1KMT2APSMB5KDM4E | |
| SCHEMBL29819601 | 0.79 | PSMB5 (0.51) | GPR119MEN1KMT2APSMB5KDM4E | |
| SCHEMBL17225154 | 0.79 | ESR1 (0.47) | GPR119MEN1KMT2AESR1ESR2 | |
| SCHEMBL8995192 | 0.78 | GPR119 (0.43) | GPR119MEN1KMT2APSMB5ESR1 | |
| SCHEMBL24205728 | 0.77 | NPC1 (0.52) | GPR119MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL12332787 | 0.76 | NPC1 (0.51) | GPR119MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL22946076 | 0.76 | SMN1; SMN2 (0.68) | TTRALBMAOACNR1DRD1 | |
| SCHEMBL2914500 | 0.76 | PSMB5 (0.46) | MEN1KMT2APSMB5KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057662-A | Synthetic method of Tafamidis | 湖南第一师范学院 | 2022-02-18 | — | — | CN | disclosed |